Table 2 Comparison of circulating levels of inflammatory chemokine ligands in patient and control groups
From: Circulating chemokine ligand levels before and after successful kidney transplantation
a | |||||
Chemokine (pg/m) | Control (n = 20) | Pre-transplant | Post-Transplant | ||
CCL1 (47/44) | 2.9 (2.0–3.8) | 7.7 (5.4–9.1) | 2.0 (2.0–2.4) | ||
CCL2 (47/45) | 231.0 ± 77.9 | 55.3 (38.9–74.4) | 108.1 (98.3–144.5) | ||
CCL3 (46/44) | 7.8 (5.3–9.0) | 2.1 (1.8–2.5) | 4.2 (3.7–4.7) | ||
CCL4 (46/44) | 118.3 (96.2–127.2) | 149.9 (128–177.8) | 47.0 (34.1–80.7) | ||
CCL5 (46/41) | 23805.2 ± 4535.9 | 12399.7 (8403.6–14469) | 3312.5 (2474.2–5636.2) | ||
CCL8 (47/44) | 27.8 ± 13.6 | 49.9 (41.4–56.7) | 25.8 ± 1 0.6 | ||
CCL11 (47/44) | 39.0 (14.9–88.1) | 192.4 (156.9–236.5) | 80.8 (39.2–130.6) | ||
CCL13 (46/42) | 44.0 ± 14.4 | 123.3 (100.2–148.5) | 37.6 (20.1–57.5) | ||
CCL15 (47/40) | 1292.0 (803.5–1453.7) | 7192.7 (5758.8–9180.9) | 3233.5 (2233.1–4466.5) | ||
CCL17 (46/43) | 34.4 (25.0–52.4) | 111.3 (65.2–162) | 20.9 (16.1–32.3) | ||
CCL21 (46/44) | 290.8 ± 80.3 | 37.9 (9.7–76.3) | 183.7 (159.2–262.3) | ||
CCL24 (47/43) | 494.7 (282.8–720.4) | 836.1 (667.4–1396.1) | 304.9 (223.1–420.9) | ||
CCL26 (47/44) | 16.7 ± 10.1 | 3.7 (3.1–4.6) | 48.8 (48.8–48.8) | ||
CCL27 (47/43) | 424.9 ± 161.3 | 1328 (1038.7–1546.9) | 816.9 ± 338.7 | ||
CXCL5 (46/41) | 511.4 (455.9–688.0) | 339.7 (243.2–410.4) | 337.9 (222.2–443.3) | ||
CXCL8 (47/41) | 28.3 ± 8.7 | 25.7 (21.6–31.9) | 11.4 (8.1–13.4) | ||
CXCL10 (46/44) | 1183.0 ± 503.1 | 1868.8 (1601.6–2537.1) | 726.8 (542.5–942.8) | ||
CXCL12 (47/44) | 2424.7 (2011.8–2816.5) | 1987.7 (1567.1–2255.8) | 2220.8 (1400.6–2687.5) | ||
CXCL13 (46/44) | 19.4 (13.1–23.5) | 13.7 (9.9–18.8) | 52.5 (33.1–60.0) | ||
b | |||||
Chemokine (pg/m) # (pre-TX/post-TX) | ∆ change | % change | P1 | P2 | P3 |
CCL1 (47/44) | -4.7 (-6.8 - -3.4) | -68.6Â % | 0.000 | 0.010 | 0.000 |
CCL2 (47/45) | 64.1 (47.8–86.6) | 113.9 % | 0.000 | 0.000 | 0.000 |
CCL3 (46/44) | 2.1 (0.8–2.6) | 90.8 % | 0.000 | 0.000 | 0.000 |
CCL4 (46/44) | -98.2 (-122.9 - -67.2) | -70.5Â % | 0.010 | 0.000 | 0.000 |
CCL5 (46/41) | -814.7 ± 9480.3 | -75.6 % | 0.000 | 0.000 | 0.000 |
CCL8 (47/44) | -23.7 (-29.6 - -15.8) | -47.9Â % | 0.000 | 0.720 | 0.000 |
CCL11 (47/44) | -97.4 (-164.4 - -61.59) | -59.8Â % | 0.000 | 0.080 | 0.000 |
CCL13 (46/42) | -72.2 ± 77.1 | -63.5 % | 0.000 | 0.720 | 0.000 |
CCL15 (47/40) | -3459.1 (-4848.2 - -1000.7) | -50.6Â % | 0.000 | 0.000 | 0.000 |
CCL17 (46/43) | -89.7 (-119.1 - -50.1) | -77.6Â % | 0.000 | 0.020 | 0.000 |
CCL21 (46/44) | 157.6 (65.1-208.2) | 404.0Â % | 0.000 | 0.120 | 0.000 |
CCL24 (47/43) | -660.1 (-830.3--535.5) | -71.0Â % | 0.000 | 0.010 | 0.000 |
CCL26 (47/44) | 44.4 (42.8–45.8) | 1096.0 % | 0.000 | 0.000 | 0.000 |
CCL27 (47/43) | -575.7 (-844.3 - -238.7) | -40.3Â % | 0.000 | 0.000 | 0.000 |
CXCL5 (46/41) | -49.1 (-218.3–41.0) | -18.8 % | 0.030 | 0.010 | 0.690 |
CXCL8 (47/41) | -10.8 (-22.7 - -7.8) | -54.9Â % | 0.720 | 0.000 | 0.000 |
CXCL10 (46/44) | -1015.3 (-1423.6 - -731.4) | -64.2Â % | 0.000 | 0.040 | 0.000 |
CXCL12 (47/44) | 133.3 (-571.7–855.5) | 4.9 % | 0.050 | 0.210 | 0.630 |
CXCL13 (46/44) | 34.1 (16.8–46.1) | 213.5 % | 0.080 | 0.000 | 0.000 |