Fig. 2
From: Acidification changes affect the inflammasome in human nucleus pulposus cells
Inflammasome signaling protein expression decreases at pathological pH. Representative immunoblot analysis (a) of caspase-1, caspase-5, ASC and XIAP at three different pH levels (7.4, 6.8 and 6.5). Densitometric analysis corresponds to the active form of caspase-1 (10 kDa, b), ASC (c) and the cleaved fragment of XIAP (23 kDa, d). β-actin was used as an internal standard for protein loading control. Data presented as mean+/−SEM. **p < 0.05 compared to 6.8 and *p < 0.05 compared to 7.4. N = 6 wells per group