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Table 1 Plasma cholesterol, non-HDL cholesterol, HDL cholesterol and plasma triglycerides at 6 weeks after saline injection or gene transfer

From: Apolipoprotein A-I gene transfer exerts immunomodulatory effects and reduces vascular inflammation and fibrosis in ob/ob mice

 

Cholesterol

Non-HDL Cholesterol

HDL Cholesterol

Triglycerides

C57BL/6

66.7 ± 7.3

15.4 ± 2.0

51.3 ± 5.9

45.6 ± 4.4

Ob/ob

144 ± 7§§§

71.8 ± 3.9§§§

72.7 ± 4.3§

51.6 ± 3.9

Ob/ob Ad.Null

153 ± 2§§§

76.0 ± 2.5§§§

77.5 ± 2.7§§

61.3 ± 5.1

Ob/ob Ad.A-I

218 ± 8§§§$$$***

87.1 ± 4.3§§§$

130 ± 5§§§$$$***

96.3 ± 11.2§§§$$$**

  1. All data are expressed in mg/dl and represent means + SEM (n = 7 for C57BL/6, n = 11 for ob/ob, n = 12 for ob/ob Ad.Null, n = 12 for ob/ob Ad.A-I). §: p < 0.05; §§: p < 0.01; §§§: p < 0.001 versus C57BL/6. $: p < 0.05; $$$: p < 0.001 versus ob/ob. **: p < 0.01; ***: p < 0.001 versus ob/ob Ad.Null