Fig. 7

The effects of Abn-CBD treatment on wound healing. HUVEC and LoVo cells were grown to confluence in 6 well plates. Then a scratch wound was made with a pipet tip. a HUVEC cells were incubated with the respective concentrations of Abn-CBD and O-1918. Wound area size was measured at 0 and 20 h. Abn-CBD significantly accelerated wound closure in HUVEC. Additional treatment with the O-1918 did not reverse this effect. b For incubation of LoVo cells, the effective dose for Abn-CBD (1 μM) was used. Wound area was measured at 0 and 20 h. Abn-CBD significantly accelerated wound closure. The Abn-CBD effect was reversed by addition of the antagonist O-1918. Data were analyzed with one-way ANOVA with Tukey’s post-hoc test. *, p < 0.05 when compared to any other treatment; n = 5-7/group