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Fig. 2 | Journal of Inflammation

Fig. 2

From: Abnormal cannabidiol attenuates experimental colitis in mice, promotes wound healing and inhibits neutrophil recruitment

Fig. 2

The effects of Abn-CBD treatment in the presence of CB antagonists on macroscopic damage score and MPO activity. TNBS-treated mice were given AM251, AM630 and/or Abn-CBD (all at 5 mg/kg) twice daily for 3 days. Macroscopic damage score (a) and myeloperoxidase activity (b) were determined at the end of the experiment, 24 h after the last dose of drug. Abn-CBD treatment and Abn-CBD + AM251 or AM630 significantly decreased the damage score. Myeoloperoxidase activity was significantly decreased with Abn-CBD. Data were analyzed with one-way ANOVA with Tukey’s post-hoc test *, p < 0.05 and **, p < 0.01 when compared to controls; n = 4-5/group

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