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Table 1 Resting and LPS(100 ng/ml)-stimulated Tissue Factor (TF) procoagulant activity (PCA), antigen(ag) and mRNA in normal (NG, 5.5 mM) and high (HG, 50.0 mM) glucose conditions

From: The effect of high glucose on the inhibitory action of C21, a selective AT2R agonist, of LPS-stimulated tissue factor expression in human mononuclear cells

TF PCA (AU)
  NG HG
Resting 0.0054 ± 0.003 0.035 ± 0.4*
LPS-stimulated (N = 33) 0.93 ± 0.36** 2.7 ± 1.1*, **
TFAg (ng/mL)
Resting 32 ± 24 428 ± 135*
LPS-stimulated (N = 12) 1486 ± 388** 2652 ± 622*, **
TF mRNA (normalized fold expression)
Resting 0.007 ± 0.003 0.158 ± 0.1*
LPS-stimulated (N = 8) 0.65 ± 0.5** 0.85 ± 0.5*, **
  1. *p < 0.001 HG vs NG, **p < 0.001 LPS- stimulated vs resting