Fig. 2
From: Role of goblet cell protein CLCA1 in murine DSS colitis
Similar inflammation and regeneration in Clca1 -/- and WT mice during DSS colitis. During DSS colitis, the a abundance of neutrophils, macrophages and lymphocytes, b the histopathology scores for erosion/ulceration and immune cell infiltration increased as well as regeneration in proximal and distal colon following a 7-day DSS colitis induction and administration of water for 2 consecutive days. No differences were observed between Clca1 -/- and WT mice. c Representative histopathology of proximal and distal colon of DSS-treated Clca1 -/- and WT mice and water controls; neutrophils (arrows), macrophages (asterisks) and lymphocytes (arrowheads). Bars: 20 μm (no DSS and insets) and 50 μm (DSS). n = 10 per group. # p < 0.05 vs. the unchallenged control group