Fig. 4
From: CFTR Knockdown induces proinflammatory changes in intestinal epithelial cells
Effect of CFTR knockdown on p38MAPK, JNK, ERK1/2 pathways in Caco-2/15 cells. Cells were incubated from 0 to 120 min with 25 ng/mL of IL1-β. Protein expression of phosphorylated p38(a), JNK(b) and ERK1/2 MAPK(c) (p-p38, p-JNK and p-ERK1/2) and total p38, JNK and ERK1/2 MAPK was analyzed by Western blotting. Data represent the means ± SEM of n = 3-9 independent experiments and the phosphorylated form expression was normalized to that of total form and reported as fold induction over basal expression. #p <0.0001 vs. scrambled-infected cells