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Fig. 6 | Journal of Inflammation

Fig. 6

From: Interleukin-18 expression increases in response to neurovascular damage following soman-induced status epilepticus in rats

Fig. 6

T-cell infiltration precedes significant IL-18 expression in damaged brain regions. Significant T-cell infiltration was observed at 24 h following GD-induced seizure activity in thalamus (a, open gray line), the CA1 (b, open black line), CA3 (b, solid black line) and dentate gyrus (b, black/gray line) though not in the piriform cortex (solid gray line, a). Increased T-cell infiltration preceded significant IL-18 expression, and no positive correlation was found between the two in any brain region (c). Data are given as cells/mm2 of tissue and reported as mean ± SEM and analyzed using a Kruskal-Wallis test with a post-hoc Dunn’s Multiple Comparison test. (n = 3 for each time point/ brain region; A: $ p < 0.05 thalamus, B: $ p < 0.05 CA1, # p < 0.05 CA3, ** p < 0.01 dentate gyrus)

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