Skip to main content
Fig. 3 | Journal of Inflammation

Fig. 3

From: Pharmacological mechanism underlying anti-inflammatory properties of two structurally divergent coumarins through the inhibition of pro-inflammatory enzymes and cytokines

Fig. 3

Effects of calipteryxin and (3’S,4’S)-3’,4’-disenecioyloxy-3’,4’-dihydroseselin on the LPS-induced iNOS protein (a), and COX-2 protein (b), iNOS mRNA (c), COX-2 mRNA (d) expression levels in RAW 264.7 macrophages using Western blotting as described in “Methods”. The data were derived from three independent experiments and are expressed as the means ± S.D. (*) p <0.05, (**) p <0.01 and (***) p <0.001 indicate significant differences from the LPS-challenged group. (###) p <0.001 indicates a significant difference from the unstimulated control group. Control (vehicle), LPS; (LPS + vehicle)-treated cells alone; TPCK 30 μM, N-p-tosyl-L-phenylalanyl chloromethyl ketone was used as a positive control

Back to article page