Fig. 3
From: Nur77 deficiency leads to systemic inflammation in elderly mice
Nur77 deletion polarizes macrophages toward a pro-inflammatory M1 phenotype. (a) The expression of Cxcl11, Indo, and Mrc1 were determined by qRT-PCR in peritoneal macrophages (MΦ) of 8-month-old Nur77+/+ (n = 6) and Nur77−/− (n = 6) mice. Error bars represent mean ± s.d. from n = 3 biological triplicates. *p < 0.05. (b) The expression of Tnfα and Il6 mRNA were analyzed by qRT-PCR in peritoneal macrophages (MΦ) from 8-month-old Nur77+/+ (n = 6) and Nur77−/− (n = 6) mice. Error bars represent mean ± s.d. from n = 3 biological triplicates. *p < 0.05 and **p < 0.01