Fig. 1
From: Nur77 deficiency leads to systemic inflammation in elderly mice
Nur77-deficient mice are more prone to develop systemic inflammation. (a and b) Gross appearances (left) and weight (right) of spleens from 2-month-old (a) and 8-month-old (b) Nur77+/+ and Nur77−/− mice (n = 6 per group). Representative images are shown. NS, not significant, *p < 0.05. (c) Hematoxylin and eosin (H&E) staining of indicated organ sections from 8-month-old Nur77+/+ and Nur77−/− mice. Representative images are shown. Scale bars, 100 μM. Original magnification, ×100. Arrowheads indicate exacerbation of inflammatory pathology