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Figure 1 | Journal of Inflammation

Figure 1

From: Pentoxifylline reduces the inflammatory process in diabetic rats: relationship with decreases of pro-inflammatory cytokines and inducible nitric oxide synthase

Figure 1

Pentoxifylline (PTX, 25, 50 and 100 mg/kg) significantly decreases glycemia in diabetic rats, after 5-day treatments. Each pair of bars represents the same diabetic group 48 h after alloxan-induced diabetes, without (untreated-diabetic rats) or with 5-day treatments with PTX or glibenclamide (GLI, 5 mg/kg). The values are means ± SD from 5 to 15 animals. a. p < 0.0002; b. p < 0.0001; c. p < 0.0313. All vs. untreated-diabetic rats (paired, two-tailed Student’s t test).

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