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Table 5 Change between baseline and 6 months in adipokine gene expression levels in peripheral blood of adult DM and JDM patients*

From: Adipokine gene expression in peripheral blood of adult and juvenile dermatomyositis patients and their relation to clinical parameters and disease activity measures

 

Adult DM

  

JDM

  
 

Baseline

6 months

Difference

P -value

Baseline

6 months

Difference

P -value

Leptin

0.66 (0.25)

0.5 (0.22)

−0.16 (0.37)

0.26

1.14 (0.29)

0.81 (0.39)

−0.34 (0.54)

0.12

Adiponectin

11.8 (17.5)

3.2 (8.72)

−8.55 (17.25)

0.20

2.04 (5.23)

6.08 (16.6)

4.04 (17.82)

0.54

Resistin

3.08 (2.65)

2.84 (4.82)

−0.24 (4.7)

0.89

1.13 (0.82)

1.44 (1.98)

0.32 (2)

0.66

Visfatin

2.25 (1.01)

2.62 (1.5)

0.37 (1.43)

0.48

1.76 (0.87)

2.24 (1.55)

0.48 (1.77)

0.47

IL-6

0.48 (0.46)

0.42 (0.24)

−0.07 (0.42)

0.67

1.23 (0.73)

0.71 (0.3)

−0.52 (0.58)

0.04

TNF-α

0.61 (0.3)

0.67 (0.4)

0.06 (0.34)

0.65

0.6 (0.17)

0.63 (0.27)

0.03 (0.29)

0.76

  1. *Values are presented as mean (SD). Gene expression levels of adipokines were normalized to the mean of age-matched controls. P-value is from paired comparison test.