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Figure 3 | Journal of Inflammation

Figure 3

From: RETRACTED ARTICLE: Valproic acid attenuates intercellular adhesion molecule-1 and E-selectin through a chemokine ligand 5 dependent mechanism and subarachnoid hemorrhage induced vasospasm in a rat model

Figure 3

Bar graph demonstrating valproic acid (VPA) on the expression of ICAM-1, VCAM-1 and E-selectin protein (western blot). Top panel represents SAH only animals (A), the vehicle-treated SAH rats (B), SAH rat treated with 10 mg/kg/day valproic acid (C), 20 mg/kg/day VPA treatment SAH rats (D) and 40 mg/kg/day VPA treatment in SAH animals (E). VPA is able to decrease the expression of ICAM-1 (at a high dose), and E-selectin (at a high dose), but does not decrease SAH induced VCAM-1 expression. The ICAM-1, VCAM-1 and E-selectin expression in the SAH group was set at 100%. All values are mean ± SD. *: P < 0.01, and #, ##, ###: P > 0.01, compared with the SAH group.

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Journal of Inflammation

ISSN: 1476-9255

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