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Figure 1 | Journal of Inflammation

Figure 1

From: RETRACTED ARTICLE: Valproic acid attenuates intercellular adhesion molecule-1 and E-selectin through a chemokine ligand 5 dependent mechanism and subarachnoid hemorrhage induced vasospasm in a rat model

Figure 1

Comparison of lumen cross-sectional areas of the basilar artery. Top panel: representative micrographs of the cross-section of basilar artery obtained from the sham operated rat (A), SAH only animals (B), the vehicle-treated SAH rats (C), SAH rat treated with 10 mg/kg/day valproic acid (VPA) (D), 20 mg/kg/day VPA treatment SAH rats (E) and 40 mg/kg/day VPA treatment in SAH animals (F). Standard bar = 200 μm. Bottom panel: quantification of the lumen cross-sectional areas. All values are mean ± SD (n = 9). Valproic acid, in 40 mg/kg/day, exerted a potential to alleviate the vasospastic response when compared with the vehicle + SAH group. *, **, ***: P < 0.01 compared with the SAH group.

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