Table 3 Relative proportions of infiltrating cells in aorta samples grouped according to presence of CKD and to the modified classification of American Heart Association (AHA)
Non-CKD | CKD | ||||||||
|---|---|---|---|---|---|---|---|---|---|
AIT | PIT | FA | AIT | PIT | FA | ||||
Mab | Location | n = 5 | n = 5 | n = 5 | p | n = 5 | n = 5 | n = 5 | p |
αCD3 | intima | 10 ± 9% | 18 ± 10% | 25 ± 5% | 0.05 | 14 ± 12% | 23 ± 11% | 33 ± 6% | 0.06 |
adventitia | 8 ± 5% | 11 ± 5% | 22 ± 11% | 0.14 | 7 ± 8% | 31 ± 31% | 23 ± 18% | 0.07 | |
αS100 | intima | 3 ± 1% | 3 ± 1% | 11 ± 7% | 0.11 | 8 ± 6% | 11 ± 8% | 16 ± 5% | 0.22 |
adventitia | 10 ± 10% | 8 ± 5% | 8 ± 3% | 0.85 | 13 ± 9% | 9 ± 5% | 9 ± 5% | 0.78 | |
αCD40 | intima | 38 ± 19% | 70 ± 15%* | 84 ± 6%t | 0.01 | 30 ± 26% | 66 ± 25% | 65 ± 12% | 0.11 |
adventitia | 61 ± 10% | 69 ± 15% | 76 ± 6% | 0.16 | 57 ± 29% | 86 ± 7% | 66 ± 16% | 0.07 | |
αCD40L | intima | 28 ± 18% | 51 ± 22% | 69 ± 31% | 0.08 | 35 ± 14% | 70 ± 20% | 51 ± 15% | 0.06 |
adventitia | 46 ± 16% | 40 ± 15% | 53 ± 14% | 0.46 | 58 ± 12% | 68 ± 16% | 40 ± 9% | 0.09 | |
αNF-κB | intima | 10 ± 18% | 49 ± 30% | 46 ± 17% | 0.07 | 19 ± 12% | 42 ± 29% | 62 ± 32% | 0.11 |
adventitia | 11 ± 11% | 58 ± 35%* | 31 ± 6% | 0.03 | 14 ± 9% | 31 ± 32% | 62 ± 18% | 0.22 |