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Table 2 Relative proportions of infiltrating cells in aorta samples from all patients classified according to the modified classification of AHA

From: Chronic Kidney Disease is associated with an increase of Intimal Dendritic cells in a comparative autopsy study

  

AIT

PIT

FA

 

Mab

Location

n = 10

n = 10

n = 10

p

αCD3

Intima

12 ± 9%

20 ± 9%

29 ± 6%t

0.005

 

Adventitia

8 ± 6%

21 ± 23%

22 ± 14%

0.02

αS100

Intima

5 ± 5%

7 ± 7%

13 ± 6%

0.03

 

Adventitia

11 ± 9%

9 ± 5%

9 ± 3%

0.97

αCD40

Intima

35 ± 20%

69 ± 17%t

73 ± 14%t

0.003

 

Adventitia

59 ± 19%

77 ± 14%

71 ± 12%

0.05

αCD40L

Intima

30 ± 16%

59 ± 22%*

61 ± 25%*

0.01

 

Adventitia

51 ± 15%

52 ± 20%

47 ± 13%

0.86

αNF-κB

Intima

14 ± 16%

45 ± 28%*

54 ± 25%t

0.01

 

Adventitia

12 ± 9%

46 ± 35%*

40 ± 18%

0.01

  1. For each case we calculated the number of CD3+, S100+, CD40+, CD40L+ and NF-κB+ infiltrating cells as percentage of total cells and expressed the result as the mean ± SD.
  2. *P < 0.05 vs AIT (Bonferroni Test); tP < 0.01 vs AIT (Bonferroni test)
  3. Abbreviations:
  4. AIT: adaptive intimal thickening,
  5. PIT: pathological intimal thickening,
  6. FA: fibroatheroma.
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Journal of Inflammation

ISSN: 1476-9255

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