Figure 1

Increased number of CD3+ T-lymphocytes and IDCs in areas of progressive ASVD lesions. A. CD3+ T-lymphocytes detected in the endothelium and subendothelial zones of aortas with PIT or FA (arrows). Magnifications as indicated. B. Box-plot showing percentage of CD3+ T-lymphocytes, regarding the total number of cells in the field, according to histological lesion. Kruskal-Wallis test. C. S100⁺ IDCs, localized in the intima of aortas according to histological lesion. Kruskal-Wallis test. Magnifications as indicated. D. Box-plot showing percentage of S-100⁺IDCs according to histological lesion. Kruskal-Wallis test. E. S100⁺ IDCs, localized in the intima of aortas grouped according to histological lesions and presence of CKD. Magnifications as indicated. F. Box-plot showing percentage of S100⁺IDCs according to CKD and with independence of histological lesion. Mann–Whitney test. In figures B, D and F, each diagram represents the median, quartiles and outliers. The colored box represents the interquartile range that contains 50% of the values. The whiskers are lines that extended from the box to the highest and lowest values, excluding outliers. A line across the box represents the median value.