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Table 1 Demographic and clinical characteristics of study subjects

From: Functional activity of peripheral blood eosinophils in allergen-induced late-phase airway inflammation in asthma patients

Characteristics Patients with allergic asthma N = 18 Patients with allergic rhinitis N = 14 Healthy subjects N = 10
Age (years), median (range) 31 (21–50) 30 (18–49) 28 (22–45)
Sex (male/female), n 10/8 4/10 3/7
Wheal diameter induced by allergen (mm), median (range) 6.2 (4–11) 7.8 ± 1.8 (4–13) 0
Sensitization to D. pteronyssinus/birch/5 grass mixture allergen, n 13/3/2 9/3/2 0
PD20 (mg), geometric mean (range) 0.38 (0.25–0.54) 0.52* 0/0/0
FEV1 (% of predicted), mean ± SD 98 ± 15 105 ± 10 102 ± 11
  1. *N = 1 because methacholine challenge provoked bronchoconstriction only to one allergic rhinitis patient.
  2. PD20 - a provocative dose of methacholine causing a 20% decrease in FEV1;
  3. FEV1 - forced expiratory volume in one second.