Figure 1From: Orphan nuclear receptor NR4A2 induces transcription of the immunomodulatory peptide hormone prolactin NR4A2 induces expression of genes involved in synovial hyperplasia and inflammation. A. K4IM human synoviocytes were transduced in triplicate with lentiviral particles containing control empty or CMV-NR4A2 expression vectors. RNA was harvested after 48 hours and NR4A2 expression was measured by RT-qPCR using GAPDH as a control. ***p < 0.001. B. Pooled triplicate cDNA from the same experiment was analyzed on TaqMan Human Angiogenesis qPCR arrays. Gene expression data was normalized to 4 housekeeping genes and the genes most highly induced by NR4A2 are displayed.Back to article page