Effects of CRMP2 silence on left ventricular fibrosis and heart function after MI in ApoE
mice. A. Representative Masson’s trichrome staining revealed left ventricular fibrosis 4 weeks after MI (magnification: 4x). Scale bar indicates 500 μm. B. Quantitative analysis of the scar area (n = 10, *p < 0.05). C. Quantification of left ventricular end diastolic diameter (LVEDd). D. Quantification of left ventricular end systolic diameter (LVESd), E. Quantification of left ventricular ejection fraction. F. Quantification of fractional shortening (n = 30, *p < 0.05 vs. control). G. Kaplan–Meier survival curves in siCON and siCRMP2 groups with MI (n = 30 per group, *p < 0.05 vs. control).