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Figure 3 | Journal of Inflammation

Figure 3

From: Silencing collapsin response mediator protein-2 reprograms macrophage phenotype and improves infarct healing in experimental myocardial infarction model

Figure 3

IRF5 was involved in CRMP2-mediated polarization of macrophages. A. Representative immunoblots showed that CRMP2 RNAi in M1 macrophages resulted in a decrease in IRF5 expression, without affecting the expression of IRF3 and IRF4. B. Representative immunoblots showed that CRMP2 RNAi in M1 macrophages resulted in decreased expression of CD86 but increased expression of CD163, which were reversed by the overexpression of IRF5. Shown are representative data from three independent experiments with similar results.

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Journal of Inflammation

ISSN: 1476-9255

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