Skip to main content
Figure 1 | Journal of Inflammation

Figure 1

From: Cellular cytokine and chemokine responses to parasite antigens and fungus and mite allergens in children co-infected with helminthes and protozoa parasites

Figure 1

The inducible and spontaneous cellular production (in pg/ml) of interleukin 10 (IL-10) (Part A), Monocyte Inflammatory Protein 3-α (MIP-3α/CCL20) (Part B) and Monokine Inducible by Interferon-γ (MIG/CXCL9) (Part C) by peripheral blood mononuclear cells (PBMC) from children is shown. Cellular cytokine or chemokine production was quantified by specific ELISA in cell culture supernatants after stimulation of PBMC for 48 hours with parasite-specific antigens from Entamoeba histolytica (Eh), Plasmodium falciparum (Pf), Ascaris lumbricoides (Asc), Schistosoma mansoni (Sm), Echinococcus multilocularis (Em), bacterial lipopolysaccharid (LPS) from Escherichia coli or allergen extracts from Dermatophagoides farinae (Df), Dermatophagoides pteronyssinus (Dp), Aspergillus fumigatus (Af) and Candida albicans (Ca). The spontaneous cytokine or chemokine releases by PBMC, i.e. cell cultures without antigen or allergen activation, are shown as baseline (Bl), and the horizontal line indicates the mean spontaneous cytokine or chemokine release. Cellular production of IL-10, MIP-3α/CCL20 and MIG/CXCL9 are shown as means with the 95% upper and lower confidence interval.

Back to article page