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Figure 6 | Journal of Inflammation

Figure 6

From: Lipopolysaccharide responsiveness in vocal fold fibroblasts

Figure 6

Downstream cytokine effects of TLR4 ligand activation. Vocal fold fibroblasts (VFF) exhibited increased expression of IL-8 after TLR4 activation. Polyp, scar, T21 and T59 VFF were seeded in 12-well plates at 2 × 105 cells/well. After 8 hrs of stimulation with 5 μg/ml of LPS, cell culture supernatants were analyzed for IL-8 expression levels. Data is graphed as the mean concentration (pg/ml) ± SD. Numbers represent a statistical significance of p < 0.001 when compared to (a) T21 (b) T59 (c) scar (d) polyp. *p < 0.05 represent differences within cell type with (w/) LPS compared to without (w/o) LPS within each cell type.

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