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Table 1 Laboratory results

From: Antioxidant and anti-inflammatory effects of selenium in oral buccal mucosa and small intestinal mucosa during intestinal ischemia-reperfusion injury

N = 6/group. Median (range)
  Small intestine Oral buccal mucosa
  Sham IR IR + selenium Sham IR IR + selenium
GSH level (pmol/mg tissue) 460 (404–580) 400 (385–455) 401 (339–427) 509 (444–555) 468 (449–540) 448 (429–478)
GSSG level (pmol/mg tissue) 397 (322–457) 382 (348–419) 447(418–467) 387 (337–438) 354 (321–399) 392 (360–416)
GPx activity (mU/mg tissue) 3.06 (2.63-3.12) 2.72 (2.34-2.94) 3.47*✝(3.20-3.82) 3.26 (2.90-3.34) 2.60*(2.30-2.77) 2.90(2.76-3.16)
MDA level (pmol/mg tissue) 118 (110–134) 1113*(849–1258) 395*✝(178–471) 41 (21–58) 119*(106–134) 94*✝(48–108)
p-IκB-α expression (OD) 1.00 (0.53-1.28) 1.87*(1.49-2.50) 1.06(0.60-1.29) 0.23 (0.07-0.35) 1.45*(1.04-2.42) 0.52(0.31-0.83)
IκB-α expression (OD) 1.00 (0.88-1.28) 0.22*(0.12-0.44) 0.92(0.68-1.56) 0.48 (0.37-0.65) 0.20*(0.20-0.36) 0.48(0.32-0.58)
NF-κB p65 expression (OD) 1.00 (0.78-1.70) 17.40*(9.93-17.69) 3.77*✝(3.63-4.62) 0.33 (0.08-0.59) 8.44*(7.15-9.93) 2.32*✝(1.73-3.16)
NF-κB p65 DNA-binding (OD) 1.00 (0.90-1.23) 2.65*(1.80-2.93) 1.62*✝(1.20-2.03) 0.47 (0.47-0.50) 0.59*(0.54-0.67) 0.51(0.47-0.54)
  Sham IR   IR + selenium  
Serum TNF-α level (pg/mL) 32.35 (31.08-34.90) 226.60 (183.46-330.04) 155.33 (129.01-203.32)
  1. GSH, Reduced glutathione; GSSG, Oxidized glutathione; GPx, Glutathione peroxidase; MDA, Malondialdehyde; p-IκB-α, Phosphorylated inhibitor kappa B-α; NF-κB, Nuclear factor kappa B; IR, Small intestinal ischemia-reperfusion injury; TNF-α, Tumor necrosis factor α.
  2. *p <0.017 vs. the sham group. p <0.017 vs. the ischemic-reperfusion injury (IR) group.