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Table 1 Laboratory results

From: Antioxidant and anti-inflammatory effects of selenium in oral buccal mucosa and small intestinal mucosa during intestinal ischemia-reperfusion injury

N = 6/group. Median (range)

 

Small intestine

Oral buccal mucosa

 

Sham

IR

IR + selenium

Sham

IR

IR + selenium

GSH level (pmol/mg tissue)

460 (404–580)

400 (385–455)

401 (339–427)

509 (444–555)

468 (449–540)

448 (429–478)

GSSG level (pmol/mg tissue)

397 (322–457)

382 (348–419)

447(418–467)

387 (337–438)

354 (321–399)

392 (360–416)

GPx activity (mU/mg tissue)

3.06 (2.63-3.12)

2.72 (2.34-2.94)

3.47*✝(3.20-3.82)

3.26 (2.90-3.34)

2.60*(2.30-2.77)

2.90(2.76-3.16)

MDA level (pmol/mg tissue)

118 (110–134)

1113*(849–1258)

395*✝(178–471)

41 (21–58)

119*(106–134)

94*✝(48–108)

p-IκB-α expression (OD)

1.00 (0.53-1.28)

1.87*(1.49-2.50)

1.06(0.60-1.29)

0.23 (0.07-0.35)

1.45*(1.04-2.42)

0.52(0.31-0.83)

IκB-α expression (OD)

1.00 (0.88-1.28)

0.22*(0.12-0.44)

0.92(0.68-1.56)

0.48 (0.37-0.65)

0.20*(0.20-0.36)

0.48(0.32-0.58)

NF-κB p65 expression (OD)

1.00 (0.78-1.70)

17.40*(9.93-17.69)

3.77*✝(3.63-4.62)

0.33 (0.08-0.59)

8.44*(7.15-9.93)

2.32*✝(1.73-3.16)

NF-κB p65 DNA-binding (OD)

1.00 (0.90-1.23)

2.65*(1.80-2.93)

1.62*✝(1.20-2.03)

0.47 (0.47-0.50)

0.59*(0.54-0.67)

0.51(0.47-0.54)

 

Sham

IR

 

IR + selenium

 

Serum TNF-α level (pg/mL)

32.35 (31.08-34.90)

226.60 (183.46-330.04)

155.33 (129.01-203.32)

  1. GSH, Reduced glutathione; GSSG, Oxidized glutathione; GPx, Glutathione peroxidase; MDA, Malondialdehyde; p-IκB-α, Phosphorylated inhibitor kappa B-α; NF-κB, Nuclear factor kappa B; IR, Small intestinal ischemia-reperfusion injury; TNF-α, Tumor necrosis factor α.
  2. *p <0.017 vs. the sham group. p <0.017 vs. the ischemic-reperfusion injury (IR) group.