Inhibition of 12-LOX reduces platelet aggregation. Platelets were pre-treated with or without 100 μM baicalein prior to aggregation with 1.25 μg/ml collagen. Platelet aggregation was measured for 6 min and data expressed as (A) area under the curve (AUC). (n = 3, mean ± SEM.). Panel B shows a representative aggregometry trace.