Hemorrhagic shock and resuscitation results in increased mouse gut permeability and bacterial translocation into mouse circulation. Mice were subjected to either sham procedure or hemorrhagic shock and resuscitation (HS/R). A. Gut permeability was assessed 30 min after completion of resuscitation. Five mice in each group, *p < 0.05 compared with sham group. B. Blood samples from sham or HS/R mice were collected at times indicated. Plasma levels of circulating LPS were determined with a Limulus Amebocyte Lysate (LAL) endotoxin assay kit. Six mice per group, *p < 0.05 compared with sham group.