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Table 2 Change of circulating inflammatory and endothelial markers

From: Comparison of inflammation, arterial stiffness and traditional cardiovascular risk factors between rheumatoid arthritis and inflammatory bowel disease

 

Control

RA

IBD

CRP, μg/mL

0.90 (9.50, 2.00)

3.8 (0.7, 7.9)***

1.70 (0.70, 4.05)*#

IL-1β, pg/mL

0.74 (0.31, 1.23)

0.87 (0.36, 2.95)*

0.71 (0.32, 1.81)

IL-6, pg/mL

0.52 (0.33, 0.80)

1.52 (0.54, 3.37)***

1.03 (0.56, 1.79)***

IL-10, pg/mL

11.4 (6.6, 18.6)

15.8 (10.7, 38.7)*

19.3 (12.5, 31.3)***

TNF-α, pg/mL

2.32 (1.46, 3.75)

3.29 (1.99, 6.10)*

3.27 (2.18, 4.22)**

MIF, ng/mL

25.7 (21.4, 33.1)

49.3 (39.5, 79.0)**

46.2 (37.6, 58.2)**

vWF, μg/mL

7.56 (5.25, 12.50)

10.83 (7.68,19.36)**

11.32 (7.75,18.15)**

E-selectin + EMP, (/μL)

154 (122, 185)

164 (129, 204)

132(109, 184)

  1. Results were expressed as median (25, 75 percentile). *, **, *** vs. control (p < 0.05, <0.01, <0.001), # vs. RA (p < 0.05). CRP: C-reactive protein; EMP: endothelial microparticles; IBD: inflammatory bowel disease; IL-1β: interleukin-1β; IL-6: interleukin-6; IL-10: interleukin-10; MIF: macrophage migration inhibitory factor; RA: rheumatoid arthritis; TNF-α: tumour necrosis factor-α; vWF: von Willebrand factor.