Figure 5

Effect of CF on Th2 cytokines (IL-5, IL-13) in the BALF and OVA-specific IgE in the serum, and immunomodulatory effects of CF on OVA-specific Th1/Th2 cytokines produced by spleen cells (described in Materials and methods). The results are expressed as the mean ± SEM (n = 5). The statistical significance of differences between the control and treatment groups was assessed by ANOVA or the nonparametric Mann-Whitney test followed by Dunnett's multiple comparison test (*P < 0.05, **P < 0.01, ***P < 0.001). N: Normal BALB/c mice, CT: Ovalbumin inhalation + vehicle, OVA + CF (50, 200 mg/kg).