Pro-oxidant status and matrix metalloproteinases in apical lesions and gingival crevicular fluid as potential biomarkers for asymptomatic apical periodontitis and endodontic treatment response

Table 1 TOS and TAS levels in tissue samples and GCF from asymptomatic apical periodontitis and controls.

	AAP	Controls	p	AAP BL	AAP AT	p
Tissue TOS (μmol H₂O₂ equiv)	29.33 ± 3.52	25.60 ± 2.74	0.006	---	---	---
Tissue TAS (mM)	1.36 (0.85)	0.42 (2.19)	0.06	---	----	---
GCF TOS (μmol H₂O₂ equiv)	2.44 ± 1.38	2.50 ± 2.33	0.46	2.81 ± 2.02	3.02 ± 2.17	0.39
GCF TAS (mM)	0.93 ± 0.68	1.34 ± 0.75	0.03	0.74 ± 0.62	1.20 ± 0.80	0.02

Values expressed as means ± standard deviation or medians (interquartile range). AAP: Asymptomatic apical periodontitis; BL: baseline; AT: after treatment.

ISSN: 1476-9255