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Figure 2 | Journal of Inflammation

Figure 2

From: Dianthus superbus fructus suppresses airway inflammation by downregulating of inducible nitric oxide synthase in an ovalbumin-induced murine model of asthma

Figure 2

DSE reduces the levels of IL-4, IL-5, and eotaxin in bronchoalveolar lavage fluid (BALF) of mice 48 h after the final OVA challenge. OVA-induced mice had significantly higher levels of IL-4, IL-5, and eotaxin in BALF. DSE-treated mice had significantly lower levels of IL-4, IL-5, and eotaxin compared with OVA-induced mice. NC, normal control mice treated with PBS only; OVA, OVA-sensitized/induced mice; Mon, montelukast (30 mg/kg) + OVA-sensitized/induced mice; DSE-100, DSE (100 mg/kg) + OVA-sensitized/induced mice; DSE-200, DSE (200 mg/kg) + OVA-sensitized/induced mice. Values are expressed as mean ± SEM (n = 6/group). ##Significantly different from NC, P < 0.01; *,**significantly different from OVA, P < 0.05 and < 0.01, respectively

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