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Table 1 Baseline characteristics of study participants (Mean ± SEM)

From: Proof of Concept: Matrix metalloproteinase inhibitor decreases inflammation and improves muscle insulin sensitivity in people with type 2 diabetes

Characteristics Control Placebo Doxycycline
Sample size 15 13 11
Age (years) 48.7 ± 3.1 54.5 ± 1.7 55.3 ± 1.9
Females (%) 5 (0.33) 2 (0.15) 2 (0.18)
Weight (kg) 79.1 ± 3.6 121.6 ± 6.4** 116.8 ± 9.7**
Total Lean Mass (kg) 52.5 ± 17.5 75.5 ± 15.3** 66.7 ± 13.8*
Total Fat Mass (kg) 20.1 ± 5.8 40.7 ± 10.3** 37.8 ± 13.3
BMI (kg/m2) 26.8 ± 0.86 39.7 ± 1.4** 37.9 ± 2.6**
Fasting Glucose (mg/dL) 90.8 ± 7.4 178.2 ± 43.8** 149.4 ± 53.4**
Insulin (uIU/mL) 4.0 ± 1.9 41.0 ± 35.1** 39.4 ± 43.2*
A1c (%) 5.4 ± 0.06 8.5 ± 0.4** 8.2 ± 0.5**
Race or ethnic group no. (%)
Non-Hispanic white 13 (87) 13 (100) 9 (82)
Black 1 (7) 0 (0) 1 (9)
Hispanic 1 (7) 0 (0) 1 (9)
  1. *P < 0.05 versus control , **P < 0.001 versus control.