Table 1 Baseline characteristics of study participants (Mean ± SEM)
Characteristics | Control | Placebo | Doxycycline |
|---|---|---|---|
Sample size | 15 | 13 | 11 |
Age (years) | 48.7 ± 3.1 | 54.5 ± 1.7 | 55.3 ± 1.9 |
Females (%) | 5 (0.33) | 2 (0.15) | 2 (0.18) |
Weight (kg) | 79.1 ± 3.6 | 121.6 ± 6.4** | 116.8 ± 9.7** |
Total Lean Mass (kg) | 52.5 ± 17.5 | 75.5 ± 15.3** | 66.7 ± 13.8* |
Total Fat Mass (kg) | 20.1 ± 5.8 | 40.7 ± 10.3** | 37.8 ± 13.3 |
BMI (kg/m2) | 26.8 ± 0.86 | 39.7 ± 1.4** | 37.9 ± 2.6** |
Fasting Glucose (mg/dL) | 90.8 ± 7.4 | 178.2 ± 43.8** | 149.4 ± 53.4** |
Insulin (uIU/mL) | 4.0 ± 1.9 | 41.0 ± 35.1** | 39.4 ± 43.2* |
A1c (%) | 5.4 ± 0.06 | 8.5 ± 0.4** | 8.2 ± 0.5** |
Race or ethnic group no. (%) | |||
Non-Hispanic white | 13 (87) | 13 (100) | 9 (82) |
Black | 1 (7) | 0 (0) | 1 (9) |
Hispanic | 1 (7) | 0 (0) | 1 (9) |