Figure 6
(A) MDA levels were significantly increased in LPS-treated rats compared to the control group. This increase was significantly reduced at 24 and 48 hours by treatment with UC-MSCs. (B) Activity of HO-1 in the lungs of LPS-treated rats at 24 hours. (C) Expression of HO-1 as measured by Western blotting analysis at 24 hours. LPS induced HO-1 protein expression and stimulated HO-1 activity in the lung tissues. Treatment with UC-MSCs further increased the expression and activity of HO-1 (*, p < 0.05 compared with healthy controls; #, p < 0.05 comparing LPS plus UC-MSCs with LPS alone).