Skip to main content

Table 1 Patients and controls characterization

From: NOD2 is highly expressed in Behçet disease with pulmonary manifestations

BAL analysis Behçet's Disease (n = 27) Sarcoidosis (n = 8) Healthy Controls
% Recovery 67 (59-77) 68 (65-74) 69 (63-76)
% Viability 95 (93-97) 94 (92-97) 92 (90-96)
Cell concentration (*106/L) 182 (150-320) ¤ 175 (110-325)¤ 120 (109-270)
Total cell number (*106/L) 23 (17-32)¤ 26 (18-40)¤ 15 (9-27)
BAL differential cell counts    
% Macrophages 74 (58-77) 77 (62-84) 65 (55-67)
% Lymphocytes 19 (14-28) ¤ 22 (17-30)¤ 9 (7.5-12)
% Neutrophils 0.7 (0.5-1.2) 1.4 (0.9-1.8)¤ 0.4 (0.2-0.6)
% Eosinophils 0 (0-0.5) 0 (0-0.7) 0 (0-0.2)
CD4: CD8 ratio 4.2 ± 0.7 (3.8-5.4)¤ 6.5 (3.6-9.8)¤ 2.3 ± 0.5 (1.4-2.9)
copy number IFNγ 2786 ± 748 (1097-3600)¤ 3247 ± 921 (2568-4500)¤ 18 ± 9.5 (12-127)
BAL Th1/Th2 ratio 4.5 ± 1.2 (2.8-5.3) ¤ 5.8 ± 4.3 (5.2-12.8) ¤ 1.3 ± 0.7 (0.5-1.9)
  1. Values are presented as median ± SD (ranges) or median (range). (¤): Significance Behçet disease versus control subjects, (P = 0.001). BAL samples from 27 BD patients with pulmonary involvement, 8 patients with sarcoidosis and 23 controls were investigated. The pulmonary arteries are the second most common site of arterial involvement, preceded by the aorta. Aneurysms are more common than thrombosis.