Table 1 Patients and controls characterization
From: NOD2 is highly expressed in Behçet disease with pulmonary manifestations
BAL analysis | Behçet's Disease (n = 27) | Sarcoidosis (n = 8) | Healthy Controls |
|---|---|---|---|
% Recovery | 67 (59-77) | 68 (65-74) | 69 (63-76) |
% Viability | 95 (93-97) | 94 (92-97) | 92 (90-96) |
Cell concentration (*106/L) | 182 (150-320) ¤ | 175 (110-325)¤ | 120 (109-270) |
Total cell number (*106/L) | 23 (17-32)¤ | 26 (18-40)¤ | 15 (9-27) |
BAL differential cell counts | |||
% Macrophages | 74 (58-77) | 77 (62-84) | 65 (55-67) |
% Lymphocytes | 19 (14-28) ¤ | 22 (17-30)¤ | 9 (7.5-12) |
% Neutrophils | 0.7 (0.5-1.2) | 1.4 (0.9-1.8)¤ | 0.4 (0.2-0.6) |
% Eosinophils | 0 (0-0.5) | 0 (0-0.7) | 0 (0-0.2) |
CD4: CD8 ratio | 4.2 ± 0.7 (3.8-5.4)¤ | 6.5 (3.6-9.8)¤ | 2.3 ± 0.5 (1.4-2.9) |
copy number IFNγ | 2786 ± 748 (1097-3600)¤ | 3247 ± 921 (2568-4500)¤ | 18 ± 9.5 (12-127) |
BAL Th1/Th2 ratio | 4.5 ± 1.2 (2.8-5.3) ¤ | 5.8 ± 4.3 (5.2-12.8) ¤ | 1.3 ± 0.7 (0.5-1.9) |