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Figure 6 | Journal of Inflammation

Figure 6

From: Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity

Figure 6

Effects of curcumin on nuclear translocation of p65/NF-κB, measured by immunoblotting of p65 (n = 3, nuclear extracts, 60 min). 6a: Nuclear translocation of p65, measured by immunoblotting (n=3, nuclear extracts, 60 min). One representative sample is shown and PARP-1/2 is used as a loading control. 6b: NF-kB DNA binding activity, measured by NF-kB transcription factor assay (n=2, nuclear extracts, 60 min: without statistical evaluation). Note that different internal controls (positive control, competition control and unspecific binding control) were used to validate the test.

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