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Figure 2 | Journal of Inflammation

Figure 2

From: Inhibition of nitric oxide synthesis enhances leukocyte rolling and adhesion in human microvasculature

Figure 2

L-NAME-elicited human leukocyte rolling and adhesion in vivo. A. Leukocyte rolling flux fraction in untreated mice (control, white bar) and L-NAME (50 mg/kg b.w., i.p.)-treated mice (black bars). ** indicates P < 0.01 difference from untreated mice (t test). # indicates P < 0.05 difference from L-NAME-treated group in the absence of functional blocking antibodies (t test). + and – indicate the presence and absence of functional blocking anti-P- and/or anti-E-selectin antibodies, respectively. Data are means ± SEM (n = 2−6; number of vessels studied = 4−13; control: n = 4; number of vessels = 7). B. Leukocyte adhesion in untreated mice (control, white bar) or L-NAME (50 mg/kg b.w., i.p.)-treated mice (black bars). * and ** indicate P < 0.05 and P < 0.01 respectively from untreated mice (t test). + and – indicate the presence and absence of functional blocking anti-P- and/or anti-E-selectin antibodies, respectively. Data are means ± SEM (n = 3−8; number of vessels studied = 4−16; control: n = 4; number of vessels = 8).

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