Figure 7

Representative hematoxylin- and eosin-stained histologic sections of rat knees and ankles on day 29. Each cohort was evaluated and examples are depicted of naïve controls (A, D, and G), vehicle-control treated CIA rats (B, E, and H) and prednisolone-treated CIA rats (C, F, and J). Images include photomicrographs of ankles (A, B, and C; 20X objective) and knees (D, E, and F; 10X objective) and knees taken with a slide scanner (G, H, and J). Inflammatory cell infiltration (arrows) is found in vehicle-control treated CIA rats.