Figure 3

Quantification and 3D rendering of inflammation obtained from¹⁹F signal in rat ankles. A. ROIs were drawn around each ankle and the tail in an image stack from a representative scan of an arthritic rat (day 15) to enable the calculation of ¹⁹F spins per slice. The reference tube containing a known concentration of ¹⁹F was used in calculations. Results are represented as the amount of ¹⁹F per slice in each of the ankles or tail, with images depicted for slices 7, 9 and 17. B. 3D rendering of spatial accumulation of ¹⁹F signal in the ankles of a representative arthritic animal (day 15). ¹H image is depicted on the left, and fused ¹⁹F/¹H image in the middle, and ¹⁹F on the right.