Intra-coronary administration of tacrolimus markedly attenuates infarct size and preserves heart function in porcine myocardial infarction

Table 2 Comparison of the effect between cyclosporine and tacrolimus on attenuating expressions of inflammatory and oxidative-stress biomarkers in left ventricular myocardium at day 14 after acute myocardial infarction

* indicated the more effective response in Tacrolimus therapy as compared with cyclosporine therapy on the changes of apoptotic, inflammatory and oxidative-stress biomarkers.
† Results from recent reported in the Int J Cardiol (2011;147:79–87) (reference no: 18).
MMP = matrix metalloproteinase; eNOS = endothelial nitric oxide synthase.

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