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Figure 6 | Journal of Inflammation

Figure 6

From: Intra-coronary administration of tacrolimus markedly attenuates infarct size and preserves heart function in porcine myocardial infarction

Figure 6

Detection of apoptotic nuclei in peri-infarcted area. A to C) showing the TUNEL examination of apoptotic nuclei (red arrows) in peri-infarct area on day 14 after AMI. D) The number of apoptotic nuclei was notably higher in AMI than in normal and AMI + tacrolimus, and significantly higher in AMI + tacrolimus than in normal. * vs. other groups, p < 0.001. All statistical analyses using one-way ANOVA, followed by Tukey’s multiple comparison procedure. Symbols (*, †, ‡) indicate significance (at 0.05 level) (n = 6 for each group). Scale bars in right lower corner represent 20 μm. HPF, high-power field (400x).

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Journal of Inflammation

ISSN: 1476-9255

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