Figure 8

a, b. Levels of Th1, Th2 and Th17 cytokines are increased in plasma of Crry^−/−EAMG. Ex vivo cytokine production from blood plasma collected at Day 63 p.i. from mock immunized WT and Crry ^−/− mice and tAChR immunized mice (WT EAMG and Crry ^−/− EAMG) was analyzed with cytometric bead arrays (CBA, BD Biosciences). Individual cytokine concentrations are shown in pg/ml. Asterisks (*) indicate values p < 0.05 between complement regulator sufficient WT and complement regulator deficient Crry ^−/− mice (Figure6a - Ctrl,Figure 6b - EAMG). Results shown are representative of three independent analyses (n = 4–6 mice per experimental group).