Hydrogen saline(range from 2.5 ml/kg to 10 ml/kg) decreased 3-nitrotyrosine(3-NT) concentration in the serum. Serum was collected 4 h after carrageenan treatment. 3-NT was measured with an ELISA(7 mice were tested per group).*P < 0.05 compared with CA+saline group. CA = carrageenan treatment. CA + saline = carrageenan and saline treatment. HS = carrageenan and hydrogen saline treatment.