Effect of treated with different dose of hydrogen saline(range from 2.5 ml/Kg to 10 ml/Kg) on carrageenan-induced paw oedema in mice. The paw swelling ratio is the percent increase of paw volume. The time-dependent curve has shown us the anti-inflammatory effect of hydrogen saline, and it significantly inhibited the ratio of paw swelling at 4 hours after carrageenan injection. Each value is the mean ± SE (7 mice were tested per group). *P < 0.05 and **P < 0.01. CA = carrageenan treatment. CA + saline = carrageenan and saline treatment. HS = carrageenan and hydrogen saline treatment.