Hepatoprotective effect of Matrine salvianolic acid B salt on Carbon Tetrachloride-Induced Hepatic Fibrosis

Journal of Inflammation

Table 4 Effect of Matrine salvianolic acid B salt on GSH, MDA and SOD in rats

Treatment	Doses (mg/kg)	GSH (mg/gprotein)	MDA (nmol/mgprotein)	SOD (U/mg protein)
Normal control	——	3.00 ± 0.14	1.03 ± 0.22	262.95 ± 30.43
CCl₄	——	1.85 ± 0.28^##	3.00 ± 0.45^##	151.95 ± 20.25^##
Matrine + CCl₄	50	2.36 ± 0.53^**	2.52 ± 0.87	151.74 ± 11.44
Salvianolic acid B + CCl₄	150	2.16 ± 0.65	2.12 ± 0.43^**	159.85 ± 22.28
	25	2.28 ± 0.59*	2.58 ± 0.62	169.94 ± 25.16
Matrine salvianolic acid B Salt + CCl₄	50	2.48 ± 0.33^**	2.11 ± 0.31^**	184.65 ± 24.90^**ab
	100	2.63 ± 0.29^**b	1.79 ± 0.43^**a	191.71 ± 48.32^**ac
Fu fang bie jia ruan gan pian + CCl₄	780	2.52 ± 0.32^**	1.76 ± 0.76^**	171.39 ± 28.90

Data is expressed as the mean±SD (n = 12).
^##p < 0.01 vs. the normal control group; ^*p < 0.05, ^**p < 0.01 vs. the CCl₄-treated group;
^ap < 0.01 vs. the Matrine group; ^bp < 0.05, ^cp < 0.01 vs. the Salvianolic acid B group.

ISSN: 1476-9255