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Table 1 Standard laboratory indices and oxidative stress-associated measures in BD patient and healthy control groups.

From: A panel of oxidative stress assays does not provide supplementary diagnostic information in Behcet's disease patients

 

Control Subjects

 

BD Patients

 

P value

ESR (1 h)

7.0 (5.0-10.0)

n = 50

11.5 (7.0-21.3)

n = 100

< 0.0001

CRP (mg/L)

0.09 (0.05-0.11)

n = 50

0.36 (0.10-2.20)

n = 98

< 0.0001

Leukocytes(103/mm3)

5300 (4800-6200)

n = 43

7250 (6100-9300)

n = 98

< 0.0001

TNF-α (pg/mL)

2.74 (1.26-3.70)

n = 33

3.43 (1.76-4.70)

n = 82

0.093

IL-18 (pg/mL)

181.4 (117.2-245.6)

n = 37

263.4 (193.9-375.3)

n = 100

< 0.0001

MPO (U/mg protein)

1.19 (0.45-2.99)

n = 37

3.86 (1.70-5.86)

n = 93

< 0.0001

e-TBARS (nmol/gHb)

27.1 (23.7-29.6)

n = 38

28.4 (25.0-32.9)

n = 100

0.175

e-SOD (U/gHb)

674.4 (417.4-913.4)

n = 38

621.4 (427.5-1026.0)

n = 99

0.838

e-CAT (U/gHb)

4711 (3968-5373)

n = 38

5105 (4419-5914)

n = 100

0.110

AOA (%)

34.9 (27.3-49.5)

n = 40

42.1 (31.8-51.3)

n = 89

0.304

FRAP (μmol/L)

864.9 (728.5-1050.0)

n = 33

773.0 (675.3-896.6)

n = 99

0.056

TEAC (trolox equivalent)

4.69 (4.01-4.98)

n = 33

4.68 (4.20-5.18)

n = 100

0.560

  1. Data are expressed as median (interquartile range) values
  2. ESR = Erythrocyte sedimentation rate, CRP = C-reactive protein, TNF-α = tumor necrosis factor-α, IL = interleukin, MPO = myeloperoxidase, e-TBARS = erythrocyte thiobarbituric acid reactive substances, e-SOD = erythrocyte superoxide dismutase, e-CAT = erythrocyte catalase, AOA = antioxidant activity, FRAP = ferric reducing antioxidant power, TEAC = Trolox equivalent antioxidant capacity