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Figure 2 | Journal of Inflammation

Figure 2

From: LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and Giα dependent PI-3kinase signalling

Figure 2

PI3K inhibition prevents C5a-induced chemotaxis in human monocytes. Human monocytes were pretreated with wortmannin for 30 min and then allowed to migrate in response to 3 nM C5a. Data was normalised relative to control, where control represents 100% chemotaxis in response to C5a only treatment. Results are displayed as mean ± SEM for 3 independent experiments and the sigmoidal dose response curve plotted using Prism4 software.

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Journal of Inflammation

ISSN: 1476-9255

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