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Table 2 A comparison of human and murine monocyte subsets, highlighting differences in surface receptor phenotypes.

From: Innate immunity and monocyte-macrophage activation in atherosclerosis

 

Human

Mouse

Classical/Inflammatory

CD14++ CD16- [195, 196]

(>90%)

Ly6C+ CCR2+ CD62L+ CX3CR1low [47, 59] (~50%)

Non-Classical/Resident

CD14+ CD16+ [195, 196]

(<10%)

Ly6C- CCR2- CD62L- CX3CR1high [47, 59] (~50%)

  1. The approximate abundance in peripheral blood is shown in brackets, however this may not reflect the proportions in other sites such as the spleen.
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Journal of Inflammation

ISSN: 1476-9255

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