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Table 2 Fold changes of genes of interest during the time-course of a healing wound in IL-12/23p40-/- and C57BL/6J mice.

From: Accelerated wound healing phenotype in Interleukin 12/23 deficient mice

Gene of Interest

Strain of Mouse

Fold-Change

  

Day 1

Day 4

Day 7

 

IL-12/IL-23p40

71.59

9.62

7.92

MCP-1

C57BL/6J

27.21

6.02

5.16

 

IL-12/IL-23p40

128.6

17.63

11.77

MCP-3

C57BL/6J

58.07

8.76

8.55

 

IL-12/IL-23p40

11235

788.3

1104

MIP-2

C57BL/6J

2073

763.9

274.5

 

IL-12/IL-23p40

3028

1296

1523

ENA-78

C57BL/6J

974.4

2037

821.8

 

IL-12/IL-23p40

953.9

86.42

215.6

IL-1β

C57BL/6J

165.0

115.7

59.11

 

IL-12/IL-23p40

247.1

24.59

14.54

IL-6

C57BL/6J

20.84

35.77

13.76

  1. Expression profile of chemokines (MCP-1, MCP-3, MIP-2 and ENA-78) and cytokines (IL-1β and IL-6) seen in the IL-12/IL-23p40-/- mice parallel the early recruitment of inflammatory cells and early establishment of an inflammatory response. Fold-changes were calculated using C57BL/6J unwounded samples as control group. Student's t-test, p value <0.05; n = 2 per strain, per time point.
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Journal of Inflammation

ISSN: 1476-9255

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