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Table 1 Exclusion Criteria for Participants

From: Elevated salivary C-reactive protein levels are associated with active and passive smoking in healthy youth: A pilot study

Criteria

Rationale

Periodontal disease

(self-reported).

There is a positive relationship between salivary CRP and periodontal disease, which could help to explain the underlying link between periodontal disease and higher risk for CAD [27].

Obesity

(based on body mass index measurement).

Obesity is a major determinant of elevated serum CRP [28].

Apparent clinical levels of depressive symptoms

(screened with the Beck Depression Inventory-2nd edition, BDI-II [24], which has been validated specifically with university students [25, 26]).

There is increasing evidence of a relationship between depressive symptoms and elevated serum CRP, putting individuals at increased cardiac risk [8]. Depression has also been shown to be related to TSE [29].

  1. The BDI-II is a standard measure of depression used in research that is highly correlated with the presence of symptoms of depression. The BDI-II clinical cut-off is used to indicate a high likelihood of a depressive clinical disorder.